Sentence examples for mediated actions of from inspiring English sources

Although we consider that the effects of these polymorphisms on the phenotypes may be related to the renal actions of serum leptin, we have not shown that serum leptin has direct effects on the kidneys and can therefore not exclude autocrine and/or paracrine mediated actions of leptin in the kidney.

Effects of inflammation on parahippocampal and rhinal glucose metabolism directly mediated actions of inflammation on spatial memory.

The mas receptor mediated actions of Ang-(1 7) can also be influenced by AT2R-related mechanisms, suggesting a complex interaction between these receptors and highlighting the molecular complexity of this system [ 39].

Thereby indicate the involvement of PPAR γ mediated action of PFE in TST induced neuropathy.

The demonstration that mCD47 enables PC-3 tumor cells to initiate spontaneous local and distant metastasis in CB17.Scid mouse that otherwise is resistant to the metastasis of the tumor cell reinforces the notion that CD47-SIRPα mediated action of macrophage probably plays a more important role than other innate immune components in determining the metastatic potential of xenograft tumors.

Highly specific antagonists suited to reveal receptor-mediated actions of neuroactive substances are not always available, and often the use of antisense oligodeoxynucleotide (ODN) strategies is the only alternative.

The relevance of the dual signalling remains unclear although the calcium signal can modify the cAMP-mediated actions of α-MSH on melanogenesis (Buffey et al, 1992).

The unaffected sIPSC parameters indicate that most of the receptor-mediated actions of Glu were indeed blocked by the applied antagonists.

To prove that the cGMP/PKG-mediated actions of BPA and E2 described in Figure 6 involved the upstream activation of a GC, we tested the effects of these compounds in ODQ-treated islets.

The indirect opioid-mediated actions of KTP-NH2 may explain why this compound retained its analgesic effects although the usual side effects of opioids were absent, which is a desired feature in next-generation pain medications.

Furthermore, CRH has a variety of complex effects on immune cells (Elenkov et al. 1999) and modulates immune/inflammatory responses through receptor-mediated actions of glucocorticoids on anti-inflammatory target immune cells (Tsigos and Chrousos 2002).