Sentence examples for mediated abrogation of from inspiring English sources

We next examined the requirement of optineurin in CYLD mediated abrogation of TNFα-induced NF-κB activation.

As shown in Figure 7C, inhibition of PI3K signaling by LY294002 led to loss of PDGF-BB mediated abrogation of toxicity induced by Tat and morphine, confirming that PI3K is a key player in PDGF-BB mediated protection against Tat and morphine.

However, pre-treatment of cells with a specific MEK1/2 inhibitor, U0126, followed by exposure to PDGF-BB and Tat-morphine did not lead to inhibition of PDGF-BB mediated protection against these two agents (Figure 7F), which suggests that PDGF-BB mediated abrogation of Tat and morphine induced toxicity was perhaps not mediated via the MAPK/ERK pathway.

This suggested that Red-Br-nos efficiently mediated abrogation of G2/M checkpoint, causing cells to enter mitosis despite compromised DNA integrity.

It is concluded that FasL-mediated abrogation of alloimmune responses can be effectively attained with BMC.

TLR4-initiated and cAMP-mediated abrogation of bacterial invasion of the bladder.

Song, J, Bishop, BL, Li, G, Duncan, MJ, and Abraham, SN. "TLR4-initiated and cAMP-mediated abrogation of bacterial invasion of the bladder". Cell Host Microbe 1, no. 4 (June 14 , 2007: 287-298.

Inhibition of PhoPQ signaling appears to contribute to most of the NO-mediated abrogation of the ATR in log phase bacteria, because the augmented acid sensitivity of phoQ-deficient Salmonella was not further enhanced after RNS treatment.

We found that shRNA-mediated abrogation of Nox4 activity results in increased cellular proliferation.

Our studies have revealed a crucial role for the DEP domain in Dvl2-mediated abrogation of SG assembly.

Antisense-mediated abrogation of EEF1A1 expression inhibits tumorigenesis and anchorage-independent cell replication in prostate tumor cells [ 70].