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Self-efficacy has been shown to mediate vulnerability to develop depressive symptoms, as well as the effect of depression on developing detrimental behavior including nicotine abuse.
Thus, it seems that the experience of positive emotions has a distinct and more central role in resilience defined as the successful adaptation, swift recovery and psychological growth in the face and recovery phase after exposure to severe adversities, while the stress-response systems appears to mainly mediate vulnerability to stressors.
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These studies are consistent with evidence of a genetically mediated vulnerability to PTSD in the context of traumatic stress exposure.
28 Some suggest that the comorbidity of PTSD with substance abuse may represent a shared genetically mediated vulnerability to psychopathology after trauma exposure.
These findings suggest that distinct genetic polymorphisms mediate differential vulnerability to cognitive and subjective sleepiness changes resulting from chronic PSD.
Current understanding of how genetic diversity mediates ecosystem vulnerability to climatic stress has a strong theoretical basis, but evidence from natural populations is rare.
Our observations endorse hypermobility as a multisystem phenotype and suggest potential mechanisms mediating clinical vulnerability to neuropsychiatric symptoms.
In neuronal cells ER-beta is localized in the mitochondria and mediates mitochondrial vulnerability to oxidative damage [ 51, 52]; it also impairs mitochondrial oxidative metabolism in mesothelioma [ 53].
The cellular expression of Bcl-2 and activated Caspases likely mediate the increased vulnerability to neuronal apoptosis during synaptogenesis [ 34].
Genetic variations, such as the low expression allele of the serotonin transporter gene, are associated with emotional processing biases, which in turn mediate increased emotional vulnerability to negative life events (Beevers, Wells, Ellis, & McGeary, 2009).
This accumulated hydraulic deterioration is largely mediated by increased vulnerability to cavitation, a process known as cavitation fatigue.
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CEO of Professional Science Editing for Scientists @ prosciediting.com