Sentence examples for mediate virus internalization from inspiring English sources
Because HAdV-F members do not contain an integrin that binds the RGD motif in their penton base protein, an as-yet-unidentified cellular-binding partner for the short fiber knob domain has been postulated to mediate virus internalization (27 ) in a manner analogous to the penton base RGD interaction.
Surface antigen preS of Hepatitis B virus plays fundamental roles in mediating receptor recognition and virus internalization.
In contrast, ablation of the Ras PI3K interaction restrained influenza virus internalization via inhibiting clathrin-independent endocytosis (Figures 1 and 3), underscoring Ras PI3K-mediated, clathRas PI3K-mediatedndocytosis as one of the key pathways of influenza virus entry, whereas clathrin-independentndocytosis is assupponeive ofe.
Co-receptors would subsequently intervene for virus internalization.
For virus internalization, cells were further incubated with virus at 37°C for 30 minutes.
In the current study, we detected enhanced DENV internalization in presence of Aedes SG extracts, but the virus internalization decreased when the salivary proteins were pretreated with sialidase.
Furthermore, when incubated with cells and virus at 4°C, to prevent virus internalization, suramin reduced virus binding to the cell with an IC90 of 6.17 µM.
Specifically, they suggest that cell surface integrin expression mediates virus entry at this post-internalization step via controlling endosomal cathepsins (proteases found in endosomes that mediate intracellular proteolysis; [ 38, 39]).
Cld-1, and possibly Cld-6 and -9 have been identified as co-receptors interacting with the tetraspanin protein CD81 to mediate the internalization of hepatitis C virus in the liver (Evans et al. 2007; Zheng et al. 2007).
Schliehe, C. et al. The methyltransferase Setdb2 mediates virus-induced susceptibility to bacterial superinfection.
Microglia mediate Aβ internalization through a nonsaturable, fluid phase macropinocytic mechanism.
