Sentence examples for mediate various effects from inspiring English sources

Different isoforms of TGF- β mediate various effects depending on the specific cellular context.

As numerous studies have documented the role of CO in mediating various effects of HO-1, 27 our data support that HO-1/CO-modulated signaling has an impact on the recruitment of myeloid cells to form the premetastatic niche primed by tumor-derived soluble factors.

GEP analyses also provided insight on molecular mechanisms that mediate the various effects of PTH in myelomatous bones.

In the diseases condition with RA, TNF-α mediates various biological effects depend on the cell types in order to progress or maintain the disease effectively.

In summary, our data indicates that, in addition to the epigenetic activity, deacetylase inhibitors act on protein folding and function which mediates various additional effects such as activation of the unfolded protein response or transcriptional and translational control of tumor suppressor genes.

Inflammation may be an important underlying etiology of MetS [ 8] through its various effects mediated by adipose tissue-derived factors, such as leptin, adiponectin, IL-6, IL-10 and etc. [ 12].

These various effects of histamine are mediated through the activation of specific histamine receptors (H1R, H2R, H3R, and H4R), which are all G protein-coupled receptors 18, 19.

Various effects of DETC on cell death are mediated by intracellular redox regulation and/or the different MAP kinase activation.

Activation of NF-κB, AP-1 and JAK3/STAT mediates various downstream pathological effects of LMP1 expression [ 5].

The modifications had various effects.

EHDs possess several domains that could potentially mediate various functions.