Organic anion transporters (Oats in animals/OATs in humans, subfamily of Slc22 drug transporters) mediate transport of endogenous and exogenous organic anions (OA) and play a major role in the uptake and/or secretion of OA in cells of various mammalian organs, mainly in the liver and in the kidneys.
The adenosine triphosphate-binding cassette (ABC) family transporters mediate transport of a wide variety of molecules across biological membranes and play critical roles in plant growth and development.
Accumulative transporters mediate transport of amino acids against an amino acid concentration gradient using secondary active transport dependent on electrochemical gradients.
In particular, the plasmodial hexose transporter, PfHT, known to mediate transport of this essential substrate to the parasite has been a promising candidate for development of inhibitors.
At least four other Na+-dependent carriers exist at the abluminal membrane: system ASC (SLC1A5) alanine, serine, and cysteine preferring, [ 104], system Bo+ (SLC7A3) for basic AAs [ 105], system N (SLC38A5) for nitrogen rich AA (glutamine, asparagine, and histidine) [ 106], and excitatory amino acid transporters (EAAT) (SLC1A1-3), that mediate transport of aspartate and glutamate [ 107].
Glucose transporters GLUT 1 and GLUT 3 mediate transport of DHA (Vera et al. 1993), whereas ascorbic acid enters cells through sodium-dependent transporters SVCT1 and SVCT2 (Takanaga et al. 2004).
Another peptide transporter family (PTS), that contain at least 9 members (PTS1-9) mediatransportoft of larger peptides (more than 3 AAs in chain) and in many tissues act primarily as an efflux pump, removing lipophilic peptides from cellular membranes.
Roozendaal, R. et al. Conduits mediate transport of low-molecular-weight antigen to lymph node follicles.
These proteins are believed to mediate transport of different substrates across plant PMs29,30,31.
We show that dynein motor machinery components mediate transport of nos mRNA in proximal dendrites.
Conduits mediate transport of low-molecular-weight antigen to lymph node follicles.
