Sentence examples for mediate translational activation from inspiring English sources

However, during the cell cycle arrest some miRNAs may mediate translational activation of specific transcripts [2].

Cytoplasmic polyadenylation is essential for the meiotic maturation of the oocyte as it mediates translational activation of mRNAs encoding mos kinase and mitotic cyclins involved in early rapid synchronous cell divisions [ 17- 20].

Synthesized compounds were evaluated as inhibitors of NF-κB and AP-1 mediated transcriptional and eIF-4E mediated translational activation as these transcription and translation factors are known to play a pivotal role in initiation and progression of cancer.

Cytoplasmic polyadenylation is essential for the meiotic maturation of the oocyte in both Xenopus and mouse, as it mediates the translational activation of the mRNAs encoding c-Mos kinase and mitotic cyclins [8].

On the other hand, ROS mediate transcriptional activation via NF- κB and translational activation via PI3K/AKt/4E-BP1 pathway [ 16].

Moreover, some microRNAs mediate target mRNA cleavage [ 4], chromatin reorganization followed by transcriptional repression or activation [ 5, 6], or translational activation [ 7, 8].

In summary, microRNA regulate target gene mostly by translational repression and sometimes through translational activation.

This did not influence the shift towards translational activation in IPF (not shown).

It is possible also that the Nanos3-3'UTR involvedved in translational activation in germ cells.

On sensing ER stress, PERK induces the phosphorylation of eIF2α and the translational activation of ATF4 [15].

In each of these systems, relatively short nascent peptide elements interact with the ribosome exit tunnel to mediate translational arrest.