Exact(4)
There are a great many varieties of mechanical receptors in animals, but best known are the receptors that mediate touch, the variety of hair cell receptors in vertebrates that mediate hearing (the acoustico-lateralis system), and the muscle spindle proprioceptors that monitor the state of muscle contraction.
It is generally recognized that C and Aδ-fibre sensory neurons convey pain signals, while neurons with larger-size fibres mediate touch sensation.
Degenerins from Caenorhabditis elegans are mechanosensitive channels that mediate touch transduction [ 11].
The situation for mechanoreceptors that mediate touch sensation in vertebrates was unknown.
Similar(55)
In the species Caenorhabditis sp. 3, only the ASH neuron was required to mediate nose touch avoidance instead of three neurons in C. elegans.
The mechanosensory neurons that mediate gentle touch responses have axon termination defects (Schaefer et al. 2000), and sensitizing genetic backgrounds have been used to reveal abnormalities in axon guidance (Li et al. 2008).
For example, the insular cortex, the main target of the CT projections and known to mediate affective touch signals [ 11, 13, 23, 24], serves important integrative functions for sensory, motor, and emotional signals and seems to be involved in maintaining the homeostatic control over the body [ 22, 25, 26].
Touch is a powerful conduit for emotional connectedness, and thus mediating haptic (touch) displays have been proposed to address this deficiency; but suitable evaluative methodology has been elusive.
It seems related to the ephaptic cross-talk between Aβ fibres mediating light touch and small-myelinated Aδ fibres close to the trigeminal nerve root entry zone, where there a focal demyelination is caused by neurovascular compression.
Ethylene mediates both touch responses [ 8] and auxin transport [ 9].
It is conceivable that in Caenorhabditis sp. 3, other neurons could be involved in mediating nose touch behavior.
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