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Despite growing recognition of the diverse roles of Bergmann glia, the molecular mechanisms that mediate these roles remain largely unexplored.
Despite growing evidence of the indispensable roles of glial cells in many aspects of nervous system development and function, much remains unknown about the molecules that mediate these roles, particularly in vivo.
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Future research should evaluate whether these mechanisms mediate the role of arsenic in diabetes development.
These results provided strong evidence that d17iso-GlcCer mediated the roles of mmBCFAs and d17iso-SPA in postembryonic development.
FGL2 prothrombinase expression may mediate the role of thrombin in human parturition.
In addition, these proteins may be involved in other cellular functions, such as mediating specific tumour signals, but these roles are not yet well understood [ 3].
This result raises several interesting questions: the underlying mechanism of amphetamine-induced premature responding, the separate roles of the core and shell in mediating these effects, and how these roles converge with associative learning elements to allow the inhibition or execution of appropriate motor programs.
However the mechanisms whereby the Mbnl proteins mediate these functions and the role of these novel functional aspects of the Mbnl proteins in disease initiation has yet to be fully understood.
Collectively, these isoenzymes are known to mediate critical roles in signal transduction, tumour promotion and cell regulation.
Xu, C. et al. Distinct hippocampal pathways mediate dissociable roles of context in memory retrieval.
Alternatively, Rho GTPase effectors could be more promising drug targets, because each of these effectors mediates specific roles of Rho GTPases.
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