Sentence examples for mediate their toxicity from inspiring English sources

Because these different toxicological models address a specific hallmark of PD, that is, mitochondrial dysfunction, oxidative stress, and dopamine toxic metabolism, understanding the molecular mechanisms that mediate their toxicity is of great importance.

However, the mechanism by which these aggregates mediate their toxicity remains unclear.

The mechanism by which aggregates of the β-amyloid peptide (Aβ) mediate their toxicity is uncertain.

However, how oxidative stress mediated their adrenal toxicity is far from clear.

Two of the QTL are located in regions of the Drosophila genome harboring the fly orthologs of human genes believed to mediate MTX toxicity (either through their being in the biochemical pathway involved in processing MTX or their harboring SNP that have been shown to have clinical effects on toxicity).

Both are markedly hyperosmotic, in the range of the complete KYWJ formulation, and their osmolality may mediate the toxicity.

Furthermore, recent reports have demonstrated that rotenone and MPP+ actually exert distinct alterations in cellular metabolism and activation of signaling cascades, supporting the idea that their toxicity is mediated by distinct mechanisms.

Further analysis is required to further identify the SRD molecules and the biological mechanism by which they mediate the toxicity associated with acute radiation sickness.

Tau, an important pathological protein of Alzheimer's disease (AD), can mediate the toxicity of amyloid β (Aβ).

YbaJ serves to mediate the toxicity of Hha.

First, SMF-1 may mediate Mn toxicity subsequent to Mn uptake at the apical membrane of the intestine, transporting Mn from endocytic compartments to the cytosol.