Sentence examples for mediate their functions from inspiring English sources

The transcription factor signal transducer and activator of transcription (STAT) 3 is activated downstream of cytokines, growth factors and oncogenes to mediate their functions under both physiological and pathological conditions.

In addition to the cooperative action of VEGF and VEGF-C, their common activation of VEGFR/2 was reported to constitute an important way to mediate their functions.

We are only just beginning to refine our understanding of the different types of endoderm and the molecular mechanisms by which they mediate their functions in development.

SLIT proteins are secreted glycoproteins that mediate their functions by binding to the ROBO.

Most gene products mediate their functions within complex networks of interconnected macromolecules, forming a dynamic topological interactome [ 11, 12].

It is plausible that multiple stress kinases employ similar downstream mechanisms to mediate their functions, and perhaps do so in a context-dependent manner.

Many proteins can bind several partners to mediate their function [2].

Since there appears to be no direct correlation between MSC engraftment and treatment response it is suggested that MSCs mediate their function through a "hit and run" mechanism[13].

The study of NSPC would be greatly facilitated by the identification of additional proteins that mediate their function and that would distinguish amongst different progenitor populations.

Little is known about how the large RH transmembrane proteins mediate their function during erythrocyte invasion, but a crucial step appears to be the proteolytic cleavage during the invasion process [14], [17].

They are sugar chains that are post-translationally attached to more than half of the total human proteins and mediate their function.