Sentence examples for mediate their effects from inspiring English sources

The opioid receptors mediate their effects mainly by inhibiting regeneration of the nerve impulse at the postsynaptic membrane.

These compounds mediate their effects via blockade of cyclooxygenase-1.

These molecules mediate their effects by binding to two proteins, called CB1 and CB2.

Many oncogenes and tumor suppressors mediate their effects by interfering with or inducing apoptotic signaling.

However, their major drawback is that they mediate their effects through activation of the PPAR-γ family of nuclear receptors.

These molecules mediate their effects through type 1 cytokine receptors, which bind cytokines with a characteristic structure.

Understanding the mechanisms by which adjuvants mediate their effects provide critical information on how innate immunity influences the development of adaptive immunity.

The model suggests that Gln45 and Tyr49 mediate their effects by interacting with RAMP1 whereas Leu41 and Ala44 are likely to be involved in binding CGRP.

The first-line treatment for lupus nephritis is the administration of glucocorticoids (GC) that mediate their effects via the glucocorticoid receptor (GR).

Both the D1 receptor and the D2 receptor mediate their effects through activation or inactivation of the 3',5'-cyclic adenosine monophosphate/Protein Kinase A (cAMP/PKA) pathway (Nishi et al. 2008).

Despite being a critical vaccine component, the mechanisms by which adjuvants mediate their effects are not fully understood and this is especially true when they are used in large animals.