Sentence examples for mediate their effect from inspiring English sources
Taxanes may partly mediate their effect in castration-resistant prostate cancer (CRPC) through disruption of androgen-receptor trafficking along microtubules.
The cis-acting regulatory sequences in the HIV enhancer that mediate their effect have also been characterized.
Several mechanisms have been proposed for the ability of tumor antibodies to mediate their effect in vivo.
These novel repressors may mediate their effect via direct / indirect regulation of SCAP, via repressing SREBP transport or by modulating INSIG1 levels.
Thus, even if the homodimer were confirmed, none of the variant residues considered would appear to mediate their effect on the biochemistry of the enzyme through destabilization of the dimer.
The functional impact of these SNPs on PIK3R1 regulation and activity is not known, however hypothesis as to the molecular mechanisms that could mediate their effect can be generated.
How aspirin and other NSAID mediate their effects is not fully understood.
They mediate their effects by responding more robustly with repeated infections.
The opioid receptors mediate their effects mainly by inhibiting regeneration of the nerve impulse at the postsynaptic membrane.
Many oncogenes and tumor suppressors mediate their effects by interfering with or inducing apoptotic signaling.
These molecules mediate their effects through type 1 cytokine receptors, which bind cytokines with a characteristic structure.
