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ATP-binding cassette (ABC) transport systems mediate the translocation of solutes across biological membranes at the expense of ATP.
In mice, the multidrug resistance (MDR) glycoproteins that mediate the translocation of phosphatidylcholine across the canalicular membrane of the hepatocyte are called MDR2.
However, we speculate that a channel such as the mitochondrial permeability transition pore (MPTP) may mediate the translocation of lysosome-like organelles into mitochondria.
This peculiar structure was shown to mediate the translocation of superhelical energy, to facilitate stabilization in the −10 bp promoter region, and to activate transcription by increasing the rate of open complex formation [54].
49 They are proposed to mediate the translocation of FAs from the extracellular milieu into cells.
E3 ubiquitin ligase Smurfs mediate the translocation of nuclear-localized I-Smads to the cytoplasm following TGFβ stimulation.
Similar(50)
Eukaryotic elongation factor 2 (eEF2) binds GTP and mediates the translocation step of translation elongation.
PARP activation can also promote apoptosis by stabilising p53, and mediating the translocation of apoptosis-inducing factor from mitochondria to the nucleus [19], [54].
PINK1 was found to reside in the mitochondrial outer membrane with its kinase domain facing the cytosol [19] and was claimed to phosphorylate cytosolic parkin, mediating the translocation of parkin to mitochondria [32].
GADD45A can induce apoptosis by mediating the translocation of Bim to the mitochondria [ 51].
The HC also mediates the translocation of the LC from the SV/endosomal lumen into the cytosol.
More suggestions(15)
facilitating the translocation
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mediate the regression
mediate the polymerization
mediate the mechanism
mediate the interconnection
mediate the justice
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mediate the trimerization
mediate the migration
mediate the dyad
mediate the majority
mediate the end
mediate the workload
mediate the dispute
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