Sentence examples for mediate the selective from inspiring English sources

It was the first molecularly well-defined HDL receptor that was shown to mediate the selective uptake of HDL lipids and HDL-dependent cholesterol efflux from cells.

The MePEG polymer surface minimizes the unspecific cell adhesion of polymer, and in the same time it helps in functionalization of polymer surface by covalent bonding of targeting moieties that mediate the selective target to specific tissues/cells by the enhanced permeability and retention (EPR) effect.

Small interfering RNAs mediate the selective degradation of target RNA by guiding a multicomponent RNAse.

Indeed, autophagy has been shown to mediate the selective degradation of NF-κB pathway components, including the IKK complex.

Atg8, and its mammalian homologs such as LC3, binds to cargo receptors including p62 to mediate the selective autophagic breakdown of ubiquitinated protein aggregates [ 13, 14].

In the kidney, tissue expression levels of drug transporters can mediate the selective filtering, retention, and excretion of renal drug and their metabolites [ 1- 4].

The CLA-1 receptor plays a pivotal role in HDL-mediated reverse cholesterol transport by mediating the selective uptake of free cholesterol as well as of native and oxidized cholesteryl esters.

Macroautophagy mediates the selective degradation of proteins and non-proteinaceous cellular constituents.

The studies described herein were designed to explore the role of Sestrin2 in mediating the selective action of leucine to activate mTORC1.

This phenomenon suggested that serum protein might play an important role in mediating the selective adhesion of cells on chiral surfaces.

Similarly, a viral intergenic ncRNA element of human cytomegalovirus (HCMV) mediates the selective down-regulation of mature miR-17 and miR-20a through sequence-specific interactions.