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These snRNPs can recognize and bind with these sites, further mediate the removal of introns and the joint of exons.
The histone trimethylation mark, H3K9me3, is recognized by chromodomain regions of HP1 and casein kinase 2 (CK2) that mediate the removal of HP1 protein [ 55].
For example, genes encoding sulfatases, which mediate the removal of sulfate from proteoglycans or lipids, are linked to several lysosomal storage diseases, including metachromatic leukodystrophy, Maroteaux-Lamy syndrome, Morquio A syndrome, Sanfilippo A and D syndromes and Hunter syndrome [ 13].
The study herein describes a novel regulatory pathway serving as a physiological switch to mediate the removal of prevailing prosurvival protein Survivin during the onset of apoptosis by the impairment of nuclear export processes that actively contributes toward the eventual demise of the cell.
We first selected K14Cre to mediate the removal of the roadblock, because K14+ epithelial cells are epithelial progenitor cells in the skin, lung, and breast epithelial basal layer, and FoxN1 is a regulator that controls skin and thymic epithelial progenitor cell differentiation.
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It mediates the removal of xenobiotic agents from living cells by a P-gp-mediated efflux mechanism, a major cause of multidrug resistance (MDR).
As well, Kindle et al. have shown that calpain is essential for mediating the removal of the CBP/p300 acetyltransferases that are essential for MOZ-TIF2-mediated transformation in AML.
The biological pump mediates the removal of carbon and nitrogen from the euphotic zone through the downward flux of aggregates, feces, and vertical migration of invertebrates and fish [1].
Cell death has an important homeostatic role, mediating the removal of damaged cells, organelles, and proteins.
Novak et al. therefore conclude that NIX is a selective autophagy receptor, which mediates the removal of damaged mitochondria.
In contrast, the effect of HAT could be antagonised by the opposing histone deacetylase (HDAC) enzymatic activity which mediates the removal of acetyl groups from lysine residues.
More suggestions(15)
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mediate the polymerization
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mediate the trimerization
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mediate the dyad
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mediate the end
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