Sentence examples for mediate the regulatory from inspiring English sources

Multiple mechanisms are thought to mediate the regulatory actions of leptin on lipid metabolism.

pDCs could potentially mediate the regulatory effect of donor apoptotic cells on anti-donor T cells, since they facilitate transplantation tolerance in mice [45] [47].

In our model, we explicitly consider the process of gene regulation by introducing gene products that mediate the regulatory connections among genes.

Consistently, the N-terminal extension was suggested to mediate the regulatory interaction with the protein AROS (active regulator of Sirt1) [ 19] and pharmacological activation of Sirt1.

Thus, simply the ability to bind Slou at a particular location in an enhancer is insufficient to mediate the regulatory activity of this FCI-HD TF.

Indeed, blocking Abs directed against TGF-β and IL-10 inhibited the regulatory activity of CD4+CD25low/-GITR+ cells partially or completely, demonstrating that both cytokines mediate the regulatory activity.

This refractoriness has been experimentally validated in the wing primordium, mediates the regulatory interplay between Notch and Wg and promotes the formation of mutually exclusive domains in terms of their activities.

SFPQ critically mediated the regulatory effects of MALAT1.

These findings support the suggestion that T3 may have an important role in mediating the regulatory effects of glucocorticoids on tissue and circulating ACE expression in utero (46).

As zebrafish Bach1b contains HRMs with CP dipeptide (Fig. 1A), it mediates the regulatory role of heme in transcription of the zymogens investigated here (Wang et al., 2007).

This suggests that ZEB1 may be involved in mediating the regulatory switch in primed pre-adipocytes toward the terminal differentiation program.