Sentence examples for mediate the rapid from inspiring English sources
They are designed to mediate the rapid and efficient transmission of signals from the presynaptic bouton of one neuron to the postsynaptic plasma membrane of a second neuron.
Voltage-gated Na+ channels mediate the rapid upstroke of the action potential in excitable tissues.
The rapid stimulation of SphK1 was dependent on activation of the PI3K/Akt signaling, which has been shown to mediate the rapid effects of androgens [39], [40].
Finally, the nervous system of earthworms in the genus Lumbricus is well known for the giant fibers that mediate the rapid withdrawal response [36], [37].
In the pancreas (tail) the high uptake (per/cc tissue) of methamphetamine could reflect uptake by dopamine transporters and vesicular monoamine transporters, which are targets of methamphetamine and are highly expressed in pancreatic tissue [20] and may mediate the rapid increases in insulin that follow acute methamphetamine administration [21].
In addition to other mechanisms that may exist, ligand activation of nuclear mGluRs expressed in HEK 293 cells is achieved via endogenous sodium-dependent transporters and cystine glutamate exchangers that mediate the rapid delivery of quisqualate or glutamate into the cell and into the nuclear lumen [17], [54].
Thus, this intracellular vesicular system mediates the rapid mobilization and secretion of preformed IL-4 by activated eosinophils.
Our data is consistent with the observation that ERβ mediates the rapid phosphorylation of CREB in OVX mice [86].
Currently, it is unclear which extranuclear estrogen receptor mediates the rapid effects of E2 or the E2 conjugates used in our study.
To determine which ER subtype was responsible for mediating the rapid stimulatory effect of E2 on [Ca2+]i oscillations, the cells were treated with ERα or ERβ-selective agonists.
Given the fact that Gr-1 antibodies are extremely efficient to mediate long-term neutropenia in mice [8], [27] one can speculate that the antibodies binding to the positively selected cells also mediated the rapid destruction of the transferred PMN, e.g. by complement mediated lysis in the host [28].
