Sentence examples for mediate the pathogenesis from inspiring English sources

IL-1β is also shown to mediate the pathogenesis of UC [ 30].

Moreover, oxidative stress has been shown to mediate the pathogenesis of neurodegenerative diseases, including PD [ 6], AD [ 32], and cerebrovascular disorders such as stroke [ 31].

Type IV secretion systems have been demonstrated to be important for virulence in other microorganisms and are thus likely to help mediate the pathogenesis of A. baumannii [ 23].

It is important to propose that IL-17 can induce IL-22 or that these cytokines may act together to mediate the pathogenesis of AIA.

For example, dietary obesity was found to induce NADPH oxidase-associated oxidative stress in rat brain [ 84], indicating that brain oxidative stress could potentially mediate the pathogenesis of overnutrition-related metabolic diseases.

Moreover, ROS have been shown to cause cellular damage or tissue injury, and then mediate the pathogenesis of various renal disorders, such as renal ischemia or nephropathy [ 7, 10].

Therefore, NF-κB mediates the pathogenesis of RA by functioning in different cell types.

Accumulating evidence indicates that T-cells reactive to gut microbiota antigens are crucial in mediating the pathogenesis of IBD.

The presence of human immunodeficiency virus type 1 (HIV-1) in the brain is believed to be responsible for mediating the pathogenesis of neurological abnormalities through the viral toxins gp120 and Tat.

In light of the central role that TGF-ß plays in mediating the pathogenesis of fibrosis, we sought to examine the possibility that it might modulate the expression of PPAR-γ, and that activated TGF-ß signaling could account for impaired PPAR-γ expression seen in SSc.

Abundant evidence indicates that PDGF and its receptors are important in mediating the pathogenesis of airway and interstitial lung fibrosis [ 25].