Sentence examples for mediate the output from inspiring English sources

These results suggest that Eomesa may mediate the output of Nodal signalling at the level of transcription through interaction with Smad2, and that the common target genes are conserved Nodal target genes in mesendoderm formation.

Prior to the recent evidence for REV-ERBα and β as part of the pacemaker machinery, nuclear receptors have been generally regarded as CCGs that mediate the output pathways of circadian clocks.

Elevated numbers of fibrocytes are present in the circulation and in the airways of these patients [10], [14], [17], [18] as a result of the release of ligands of the C C chemokine receptor 5 and other cytokines that are known to mediate the output of fibrocytes from the bone marrow and their recruitment to the inflamed tissue [18], [19].

The simplest form of TCS is composed of a sensory histidine kinases (His-kinases), which senses signal input, and a response regulator (RR), which mediates the output of a response.

Once bound, TFs mediate the transcriptional output of the enhancer in a number of ways, including interactions with the basal transcriptional machinery at the promoter of the target gene which helps recruit RNA polymerase II (activators) (Kadonaga 2004) or by preventing the binding of additional protein factors at closely located binding sites (short-range repressors) (Small et al. 1991).

"... Here, we use a modeling approach to investigate whether and how the morphology of the basal tree mediates the functional output of neurons.

This residue (Ser-127 in mammalian YAP) is a conserved Lats phosphorylation site that has been shown to mediate the growth-suppressive output of the Hippo signaling cascade in vivo (Zhao et al., 2007).

Amygdala reactivity was also inversely associated with depression severity and was found to mediate the relationship between cortisol output and depression severity.

The PAM states that V1 or extrageniculate projections to the posterior parietal cortex of the dorsal visual pathway mediate motor output whereas projections from V1 to the inferotemporal cortex of the ventral visual pathway mediate conscious visual judgments.

As the primary excitatory neurotransmitter in the central nervous system, the amino acid glutamate mediates synaptic output from the majority of projection neurons in the brain, including pyramidal cells of the neocortex and hippocampus.

Receptors detect the extracellular inputs, and then activate signal transduction networks that mediate specific output responses such as the transcription of genes (short-term response) or cellular morphological changes (long-term response).