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SATB1 was also reported to mediate the long range chromatin associations in the TH2 cytokine locus, suggesting that the polymerization of SATB1 generates stable structure besides the binding to chromatin fragments as a transcriptional factor [20].
The LTR/POL II complex of this ERV appears to mediate the long range transfer of proteins from the LTR to the ß-globolin gene.
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March hopes these results will translate to orally dosed treatments for type 1 diabetes that cost just pennies a day, to potentially mediate the long-term effects of the disease.
Asked on Sunday whether that meant Trump wanted to mediate the long-running border dispute between Pakistan and India, Pence acknowledged recent violence in the Kashmir region and said Trump wanted "continued U.S. engagement" with both sides.
Furthermore, the specific epigenetic changes that mediate the long-term consequences of early (intra-uterine or postnatal) experience are only beginning to be recognized.
Finally, they suggest that future studies elucidate variables that moderate and/or mediate the long-term effectiveness of childhood obesity treatment programs [i.e., environmental or psychological factors; [ 7]].
DNA methylation is believed to mediate the long-term regulation of gene expression [ 13], and it is therefore interesting to note that sex differences appear to be mediated via mechanisms other than DNA methylation.
In honey bees (Apis mellifera), Vitellogenin (Vg), a yolk protein precursor, has been implicated in mediating the long lifespan and high fecundity of queen bees.
On the other hand, previous studies indicate that hyperglycemia induces excessive generation of superoxide and other reactive oxygen species (ROS) in several tissues, including the vascular endothelium, the retina and kidneys [ 17- 19] and that excessive ROS generation mediates the long term complications of diabetes in these organs.
Dopaminergic mechanisms mediating the long-term expression of locomotor sensitization following pre-exposure to morphine or amphetamine.
The influence of the extent of hydrogen bonding in mediating the long-range connectivity and percolation of the hard segment phase in model tri-segment oligomeric polyurethanes (PU) was explored by using LiCl as a molecular probe.
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