Sentence examples for mediate the inflammation from inspiring English sources

Multiple proinflammatory mediators, including IL-1, TNF-α, interferon-γ, and MMPs mediate the inflammation of the joints.

In particular, RNF13 regulates muscle regeneration by mediating the inflammation phase.

These results indicate that MST2 mediates the inflammation during the early phase of RD.

The data with the H4R-deficient mice point to a role for the receptor in mediating the inflammation seen in the CAIA model.

MSU crystals induce secretion of interleukin-1β (IL-1β), a proinflammatory cytokine that mediates the inflammation that is characteristic of Gouty Arthritis flares and that may remain present between flares [ 3, 4].

IL-22 is secreted by Th17 cells and is highly present in various autoimmune diseases, but whether IL-22 is mediating the inflammation itself, or is a byproduct of the inflammation is depending on the tissue and overall cytokine setting [ 31].

Other investigations on prostate cancer found that pomegranate polyphenols, ellagitannin-rich extract (PE) made from fruit skins standardized to ellagitannins, can restraint prostate cancer cell caused by chronic inflammation via suppressing NF-κB pathway, which is well-established signaling pathway mediating the inflammation relevant to cancer [ 14].

It appears that IL-6 or IL-8 may not be involved in mediating the inflammation-induced Ca2+ store expansion in airway epithelia.

Since OLP occurs in constantly renewing epithelium continuously exposed to commensals, we hypothesised that the epithelial cell microflora interactions may mediate the persistent inflammation.

In turn, these pro-inflammatory cytokines are thought to mediate the synovial inflammation and cartilage degeneration seen in osteoarthritis [50].

Thus, the upregulated expression of the local proinflammatory cytokine pathways could mediate the local inflammation and functional alteration of the CB in chronic IH associated with OSA conditions.