Sentence examples for mediate the increases from inspiring English sources
These experiments were designed to determine if declining 5-HT levels observed during REMSD might mediate the increases in avoidance responding observed in REM sleep deprived rats.
Currently, the active metabolites, associated receptor, and signaling pathway(s) that mediate the increases in cortisol synthesis and gene expression observed in this study have not been identified.
Low cytokine levels suggest that these factors do not mediate the increased bone resorption of AN. (J Pediatr 2002 141 64-70).
We speculate that the signal(s) that mediate the increase in VEGF expression is present in either the fetal urine or the fetal lung secretions, or both.
Conclusion: The up-regulation of vascular endothelial growth gene expression may mediate the increase in the intramembranous absorption that is induced by volume-loading diuresis; however, this does not occur by passive mechanisms.
Watanabe et al. report that Nox4 NADPH oxidase catalytic moiety and the subunit p22phox mediate the increase in oxidative stress and human tubular epithelial cell injury induced by p-cresyl sulfate, a protein-bound uremic toxin.
Increased nerve branching appears to mediate the increase in synapse formation, which occurs following blockade of neuromuscular transmission.
MAPK pathways including ERK and p38 have been reported to mediate the increased H3 Ser 10 phosphorylation, but not decreased H3 Ser10 phosphorylation [9], [35].
To further elucidate whether increased levels of IRFs mediate the increase in TRAIL transcription, we transfected IRF-1, IRF-3 or IRF-7 siRNA, and a nonspecific siRNA as a control in MDM cultures.
Moreover, these findings suggest that epigenetic changes serve as a steward of cellular memory of aberrant intrauterine environments, and that site-specific changes in DNA methylation may mediate the increased susceptibility to age-related diseases observed later in life.
Other studies have shown that wild-type APP is not directly involved in modulating calcium stores but does mediate the increase in store size that is seen with certain PS mutants and PS deficiency [39].
