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However, when implanted, the topology and ligand landscape of the material will determine the host molecules that bind and the type and behavior of cells that mediate the host response.
These proteins transcriptionally regulate human genes that mediate the host response to bacterial invasion such as chemokines and cytokines.
Each of these segments is found to be flanked by murine endogenous retroviral (ERV) elements which have been known to mediate the host recombination [ 29].
They mediate the host response to Gram-positive bacteria and play a fundamental role in pathogen recognition and activation of innate immunity.
Therefore, microRNA profiles might have utility as biomarkers of smoking-related lung diseases and clarify the regulatory mechanisms that mediate the host response to exposure to tobacco smoke and other environmental agents.
Pathogen survival in alveolar macrophages is achieved through a diverse range of mechanisms including the inhibition of phagosome maturation and the suppression of key immuno-regulatory pathways that mediate the host immune response to infection [ 12, 13].
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Many bacterial surface exposed proteins mediate the host-pathogen interaction more effectively in the presence of Ca2+.
However, the role of single skin bacterial species in the production of volatiles that mediate the host-seeking behaviour of mosquitoes has remained largely unknown.
The role of single skin bacterial species in the production of volatiles that mediate the host-seeking behaviour of mosquitoes has remained largely unknown and is the subject of the present study.
Our observations support the finding that viral-induced PKR activation may play a significant role in pathogenesis by mediating the host response to viral CNS infection.
Cumulatively, these findings suggest that MC, even in the absence of opsonins, can directly recognize M. tuberculosis and its Ags and have the potential to play an active role in mediating the host's innate response to M. tuberculosis infection.
More suggestions(15)
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