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The genes described in this report are thus excellent potential candidates to mediate the genetic differences in adrenal steroidogenesis, particularly those affected by genotype and ACTH.
To identify candidate transcription factors (TFs) that mediate the genetic reprogramming involved in LV remodeling in the pig, we took an unbiased molecular approach (Fig. 1).
In the current manuscript, we utilized computational and bioinformatics approaches to identify regulatory mechanisms that may mediate the genetic response to iron deprivation.
Based upon these findings, we propose that SP1 or an SP1-like factor may work synergistically with one or more of these other TFs to mediate the genetic response to iron-deprivation.
To test the performance of our method on this type of pathways, we used it to infer the pathways that mediate the genetic information processing pathways from Gpa1 to Prp39.
Here we reveal that the same enzyme is also able to mediate the genetic incorporation of seven ortho-substituted phenylalanine derivatives, which brings the total substrate availability of this enzyme close to 40 and leads to the conclusion that PylRS N346A/C348A) is able to recognize phenylalanine derivatives with a substitution at any side-chain aromatic position as a substrate.
Similar(54)
The homologous clpC/ctsR flanking regions may have mediated the genetic exchange of the first 3 genes of RD53.
Altogether, our data indicate that the NLSB domain, albeit not the CASB domain, mediates the genetic interaction between imp-α2 and imp-β.
However, when M mediates the genetic risk for EOC, conditioning on M should substantially reduce the effect of G on Y [ 16, 45].
We took an unbiased molecular approach to identify candidate transcription factors (TFs) mediating the genetic reprogramming involved in post-MI LV remodeling in swine.
Nonetheless, taken together these results along with the fact that ANRIL is expressed in cells and tissues that are affected by atherosclerosis [ 27, 40] and are correlated with atherosclerosis severity [ 25, 26], they suggest that ANRIL plays an important role in mediating the genetic effect of the Chr9p21 region on the susceptibility of atherosclerosis.
Related(20)
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