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Pavilions mark the ends of the aqueduct lines and mediate the flow of water from aqueduct to park basin.
The environments organize large groups of people and facilitate a well-conceived workflow that faces four key challenges: 1) mediate the flow of information among humans toward a practicable solution; 2) motivate and retain participation on a massive scale; 3) resist surreptitious manipulation; and 4) obtain specialized knowledge when needed.
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In their detailed theoretical discussion of how to define tool use in the animal and human behavioural literature, St. Amant & Horton also revised Beck's now classic definition of tool use to include those instances of tool use which "mediate the flow of information" between the tool user and the environment, including both direct physical interactions with objects, and communicative gestures.
Membrane proteins, including membrane associated proteins, are the gatekeepers of the cell and selectively mediate the flow of information and nutrients between the outside and inside of the cell.
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secY (Rv0732) is significantly more useful as a drug target since it has been involved in the emergence of resistance in the interactome by mediating the flow of information from the existing drugs to the resistance machinery.
Since there is little or no direct interaction between the researchers studying the data and samples and the participants who donated them, the biobank (including its staff, policies and physical architecture) acts as an intermediary, mediating the flow of material between participant and researcher.
These proteins are predicted to be involved in mediating the flow of information from the targets to the resistance machinery.
Like the calcium signaling mediated by the TCR/MHC complex with force-regulated affinity on T cells (Liu et al., 2014), this force-dependent calcium signaling might be relevant to the "catch bond" mechanism that mediates the flow-enhanced roll and adhesion through a stabilizing interaction of selectin with PSGL-1 (Ling et al., 2014; Li et al., 2016).
To elucidate the reasons for the above inconsistency, we repeated the computational signal flow analysis and we found out that the only node able to mediate the signal flow from IGF-1R to Erk1/2 is β-arrestin.
Hepatocytes, the main epithelial cell type of the liver, function like all epithelial cells to mediate the vectorial flow of macromolecules into and out of the organ they encompass.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com