Sentence examples for mediate the fission from inspiring English sources
DLP1 is predicted to mediate the fission of peroxisomes and mitochondria via the formation of large multimeric spirals, in a molecular machinery similar to that of dynamin at the site of endocytosis (Danino and Hinshaw, 2001; Ford et al., 2011; Zhang and Hinshaw, 2001).
ESCRTs are multi-subunit complexes, highly conserved from yeast to mammals, which mediate the bending and fission of membranes [ 18].
ITSN is a scaffold and regulator of the general endocytic machinery; through its strategic location at the neck region of caveolae and ability to bind simultaneously more dynamin-2 molecules, ITSN recruits dynamin-2 and regulates its GTPase and oligomerization activity at the neck region of caveolae, mediating the membrane fission process and caveolae internalization.
Mitofusins and Drp1 mediate the initial steps of mitochondrial fusion and fission, respectively.
Recently, fission has been shown to mediate the clearance of damaged mitochondria by autophagy, a recycling programme for impaired and defective cellular components.
Mitochondrial fission and fusion rely on the function of multiple proteins that mediate the remodeling of the outer and inner membranes [27].
In mammalian cells, mitochondrial fission and fusion rely on multiple proteins, such as the dynamin superfamily, which mediate the remodeling of the outer and inner mitochondrial membranes [27].
These data suggest that Mtfr1 participates in mediating the signal for mitochondrial fission and apoptosis in the heart.
This finding suggested that the increased Drp1 is recruited to punctuate spots on the mitochondrial surface to mediate mitochondrial fission.
The glucose-sensing G-protein-coupled receptor Git3p (Welton & Hoffman, 2000) mediates the lifespan-shortening effect of glucose in the fission yeast Schizosaccharomyces pombe (Roux et al., 2009).
Dynamin GTPases are known to function through the formation of homo-oligomeric complexes to mediate membrane fission or fusion (52, 54).
