Sentence examples for mediate the exit from inspiring English sources

As the name implies, CKIs such as p21, p27 or p19 mediate the exit of the cell cycle through inhibition of cdk activity.

A recent study observed that mice with mutations in the Npc1 and Npc2 gene, which transcribe proteins that mediate the exit of lipoproteins from lysosomes, demonstrate striking retinal degeneration, upregulation of autophagy and marked lipofuscin accumulation within the RPE [ 18].

Previous studies suggested that CCR7 down-regulation combined with S1P signaling mediate the exit of T cells from LNs for recirculation and immune responses [11], [32].

GLUT2 mediates the exit of monosaccharides from the enterocytes and SGLT1 and SGLT4 are responsible for the uptake of monosaccharide [ 35, 62, 63].

In addition to promoting SC proliferation, cyclic AMP signaling also mediates the exit of SCs from the cell cycle by way of their transformation into a premyelinating phenotype [ 36].

CP has indeed been reported to carry nuclear export signals as well, and to mediate the nuclear exit of viral DNAs [ 10, 42, 43], which move within the plant in both their ss and ds forms [ 9].

Iron exits the enterocyte through the efflux transporter ferroportin 1 (FPN), the only member of the SLC40 family of transporters and the first reported protein that mediates the exit of iron from cells [ 40].

A combination of biochemical and immuno-EM approaches revealed that AP-3 mediates the exit of lysosomal membrane proteins from the early endosome-associated tubules, most likely for transport to late endosomes or lysosomes (dell'Angelica et al. 1998; Peden et al. 2004) (Fig.  3b).

Both structures are involved in osmoregulation and the maintenance of cell turgor during volume expansion in rapidly growing cells, mediating the rapid entry or exit of water in response to abrupt changes in osmolarity.

Analysis of state-space transitions identified potential triggers that might mediate exit from the stem cell state and highlighted a previously unrecognized inhibition of Fli1 by Gata1, which was subsequently validated experimentally.

Evidence from S. cerevisiae has shown that the Cdc14 phosphatase dephosphorylates Cdh1 to mediate mitotic exit [48].