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In cultured cell lines, several amino acid-responsive genes such as ASNS (Asparagine synthetase) [6], [7], [8] and CHOP (C/EBP homologous protein) [9], [10], [11] have been reported to contain AAREs (Amino Acid Response Elements) that mediate the enhanced transcription and function as enhancer elements [10].
However, the mod-1 serotonin receptor that has been shown to mediate the enhanced slowing response does not promote the one-hour dwelling starvation response (Fig. 4).
Figure 2 showed that only the expression of LukS-PV signal peptide can mediate the enhanced bacterial attachment to ECM proteins.
In these experiments we used the Kv2.1-C1a peptide which corresponds to the syntaxin binding domain shown to mediate the enhanced DCVs' release [21].
Therefore, MOD-1 does not mediate the enhanced dwelling after starvation that is controlled by serotonin and this behavior may then be different from the "enhanced slowing response" [11].
To establish the ability of CIITA to mediate the enhanced production of HIV protease, cells were transiently co-transfected with either CIITA or pcDNA and HIV-1NL4-3 DNandand were treated with 80 nM of Lopinavir to inhibit the majority of Gag polyprotein processing.
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Wiegand, H.L., Lu, S. & Cullen, B.R. Exon junction complexes mediate the enhancing effect of splicing on mRNA expression.
Thus, AUF1 is one key factor mediating the enhancing effect of IL-17 on IFN γ and TNF α-induced iNOS expression by MSCs.
Thus, SR proteins specifically bind exon 23 ESE and could mediate the enhancing activity of D90 observed in the heterologous Dpy2 construct.
This supports the notion that Fas does not mediate the abnormally enhanced in vivo death of cwLckCre-CAMLfl/fl thymocytes, but instead suggests that these cells have a more general aberration in survival that renders them more sensitive to Fas stimulation in vitro plus other death stimuli.
We then turned our attention to test whether only moDC mediate the enhancing effect after CpG-B adjuvantation.
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