Sentence examples for mediate the elimination from inspiring English sources

The efficiency of scavenger receptors depends on their capability to mediate the elimination of a stoichiometric multiplicity of ligands from the surrounding environment.

Most CTL expressing antigen specific receptors (TCRs) mediate the elimination of tumor cells by recognition of antigen in the form of individual peptides bound to MHC molecules [ 23, 24].

In the literature, two main processes have been described to mediate the elimination of unfit/polarity-deficient cells from Drosophila imaginal epithelia: Cell Competition (CC) and Intrinsic Tumour Suppression (ITS) [ 9].

Importantly, we found that silencing BMI1 in CD133+ cells derived from 3 PDOX models did not affect most of the known genes previously associated with the activated BMI1, but modulated a novel set of core genes, including RPS6KA2, ALDH3A2, FMFB, DTL, API5, EIF4G2, KIF5c, LOC650152, C20ORF121, LOC203547, LOC653308, and LOC642489, to mediate the elimination of tumor formation.

Phagocytosis, the engulfment of particles, mediates the elimination of invading pathogens as well as the clearance of apoptotic cells.

While autophagy was originally viewed as an inducible cellular mechanism to provide an energy source during short-term starvation, it has subsequently been shown that constitutive autophagy mediates the elimination of protein aggregates or damaged organelles and thus plays a protective role in multiple cell types [2], [3].

Parkin mediates the elimination of the defective mitochondria by autophagosomes [ 129].

It is possible that STAT1 confers this role by mediating the elimination phase of immunoediting.

This indicates that, once ESCs have exited the ground state of pluripotency, Lif is less efficient at signaling and suggests that, although events downstream of Lif may be mediating the elimination of Bmpr1a− / − ESCs, Lif itself is not directly involved in cell competition.

In the retina, when [H]E17βG was injected into the vitreous humor, its subsequent elimination from the vitreous humor/retina across the BRB was carrier-mediated, and the elimination was completely inhibited by the presence of probenecid, while digoxin had a much weaker effect [ 5].

Drug transporters mediate the uptake and elimination of drugs in various organs; therefore, having knowledge of how a transporter functions in the body would play a key role in ensuring drug efficacy in in vivo systems.