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They are important in some solar cells because they mediate the conversion of light into charge.
PqsB, PqsC and PqsD are probable 3-oxoacyl- acyl carrier protein) synthases and they mediate the conversion of anthranilate into 2-heptyl-4-quinolone (HHQ) by incorporation of β-ketodecanoic acid (Deziel et al., 2004; Gallagher et al., 2002).
Genes crtW and crtZ were amplified from the plasmid pAK96K (Misawa et al. [1995]), which harbors both the A. aurantiacum crtW (β-carotene ketolase) and crtZ (β-carotene hydroxylase) genes, and was shown to mediate the conversion of β-carotene into astaxanthin in recombinant E. coli cells.
Similarly, other studies have shown that HR between transposon elements can mediate the conversion of broken dicentric chromosomes to rearranged monocentric chromosomes [33], [35], [41].
CD40−/− DCXAbs did not mediate the conversion of T regulatory cells to IL-17+ effector cells (Fig. 3C) suggesting the necessity of IL-6 in this process.
The Erwinia genes encoding phytoene synthase (CrtB), phytoene desaturase/carotene isomerase (CrtI) and lycopene beta-cyclase (CrtY) mediate the conversion of geranylgeranyl diphosphate (GGPP) into β-carotene (Figure 1A).
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Wang, Y. et al. Comparative RNA-seq analysis reveals potential mechanisms mediating the conversion to androgen independence in an LNCaP progression cell model.
This was elegantly demonstrated in mice by silencing hepatic gene expression of diacylglycerol O-acyltransferase 2 (Dgat2), a key enzyme mediating the conversion of free fatty acids to triglyceride34.
Autotaxin is a secreted lysophospholipase that mediates the conversion of lysophosphatidyl choline (LPC) to lysophosphatidic acid (LPA), a bioactive lipid mediator.
β-carotene ketolase (crtW genes) converts β-carotene to canthaxanthin, with echinenone as an intermediary step; whereas β-carotene hydroxylase (crtZ genes) mediates the conversion of β-carotene to zeaxanthin, via β-cryptoxanthin.
We assume that this series of conformational changes reveals the structural basis mediating the conversion between closed and open states.
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