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We have argued that changes in BNST PACAP signaling may mediate the changes in emotional behavior and dysregulation of the HPA axis associated with anxiety and mood disorders.
Objective To characterize the effects of nimesulide (NIM) on basal and induced cyclo-oxygenase-2 (COX-2) gene expression in human synovial fibroblasts (HSF) and to define the intracellular mechanisms that mediate the changes in COX-2 expression and synthesis in response to the drug.
Changes in the localization and regulation of these receptors in turn mediate the changes in synaptic efficacy that occur during learning and memory [2].
Sleep alterations found in narcolepsy and idiopathic hypersomnia, such as disturbed or excessive sleep, could mediate the changes found in narcolepsy or idiopathic hypersomnia.
Moreover, histone modifications are expected to mediate the changes of gene expressions caused by electro-acupuncture treatment.
Among many factors, inflammatory cytokines and proteases are main contributors which mediate the changes in the quality of ECM [ 2].
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In some virus capsids, subtle changes in the contacts are supplemented by structural switches that mediate the change from hexameric to pentameric assembly (Johnson and Speir, 1997).
Alternatively, lifestyle factors that were unaccounted for in this study may mediate the change in triglyceride and/or the associated modification of diabetes risk.
The key aim was to determine whether a change in alcohol-related attentional bias (produced by devaluation) would mediate the change in alcohol choice, thereby indicating whether attentional bias for drug cues plays a causal role in drug-seeking.
Taken together, we hypothesize that compared to RT (i) IBMT will produce greater creativity (indexed by TTCT) (ii) IBMT will improve emotion (indexed by PANAS scales) and (iii) this improved emotion may mediate the change in creativity.
Experiments were designed to differentiate the mechanisms of bradykinin receptors mediating the changes in intracellular Ca2+ concentration ([Ca2+]i) in canine cultured corneal epithelial cells (CECs).
More suggestions(15)
mitigate the changes
resolve the changes
negotiate the changes
reconcile the changes
regulate the changes
communicate the changes
mediate the changing
mediate the altered
mediate the shift
mediate the modification
mediate the morphologies
mediate the effects
mediate the circumstances
mediate the talks
mediate the findings
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com