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To understand how dynamic geometry environments mediate the activity of mathematics teachers, we used Rabardel's categories of tool mediations in an instrument-mediated activity.
We took the stance that students and the teacher brought previous individual and collective experiences to viewing video, as is the case for all classroom experiences, and these experiences mediate the activity of video watching.
In what follows, we discuss our results in the context of the existing literature and speculate on what pathways mediate the activity that persists following the V1 lesions.
Whilst we have not confirmed this here because of a lack of an antibody for ETV6/7 which works well in ChIP, the ETV6/7 (TEL1/TEL2) proteins are still likely candidates to mediate the activity of this repressor element.
Heparan sulfate is a major physiological player at the cell-extracellular matrix interface where it has been shown to interact with and mediate the activity of a number of proteins.
Since then, Rac1 has been reported to promote reactive oxygen species (ROS) production in many cells and to mediate the activity of the Nox family [ 137, 138].
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Those genes produce complement regulatory proteins that normally mediate the activities of complement, a system of proteins responsible for the breakdown of immune complexes and defense against infection.
We firstly examined whether cystatin C may mediate the activities of MAPK and TGFβ pathways by regulating the expression and phosphorylation of Smad2 and Erk1/2 in PC3 cells.
Recently Kovacs et al. (2008) reported that beta-arrestins are required to mediate the activity-dependent interaction of Smo and the kinesin motor protein Kif3A in the primary cilium [ 54].
The role protein-protein interactions in mediating the activity of the individual domains will also be discussed.
Drawing on Roth and Lee's (2007) review of Vygotsky's neglected legacy of cultural-historical activity theory, we wondered, how the object (a video) mediates the activity (video watching) realised by students.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com