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Interestingly, siRNAs do not spread from cell to cell in Drosophila (Roignant et al., 2003), in contrast to the mechanism by which RNAi molecules are directly distributed in plants (Palauqui et al., 1997; Winston et al., 2002) and nematodes (Fire et al., 1998; Voinnet et al., 1998) to mediate systemic immunity.
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Wendehenne, D., Gao, Q.-m., Kachroo, A. & Kachroo, P. Free radical-mediated systemic immunity in plants.
Wang, C. et al. Free Radicals Mediate Systemic Acquired Resistance.
Although C. elegans has no adaptive immune system, it has comprehensive systemic immunity.
Furthermore, treatment stimulated an initial non-specific immune reaction that lead to a systemic immunity.
Mucosal immunity consists of innate and adaptive immune responses which can be influenced by systemic immunity.
Spitzer, M. H. et al. Systemic immunity is required for effective cancer systemic immunity is required for effective cancer immunotherapy.
Delivery of vaccines via the pulmonary route has been shown to induce mucosal and systemic immunity.
The induction of effective mucosal immunity that also provides systemic immunity is a considerable challenge.
Our results show that the membrane-anchored flagellin-containing VLPs induce enhanced antigen-specific systemic immunity.
- 'also exhibit local immunity': 'Also' seems weird when the part above discusses systemic immunity.
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CEO of Professional Science Editing for Scientists @ prosciediting.com