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The short-wavelength-sensitive (SWS1) pigments mediate sensitivity to light in the violet to UV range.
To determine the mechanism for the ability of Metnase to mediate sensitivity to Topo IIa inhibitors, we investigated whether Metnase levels affected the cellular apoptotic response to adriamycin.
Interestingly, glucosylceramides appear to mediate sensitivity to heat stable antifungal factor (HSAF), as, in addition to ΔBAR1 mutants, a glucosylceramide synthase deficient mutant of Yarrowia lipolytica is also resistant to HSAF.
Trigeminal expression of TRPM8 mediates sensory input from cold stimuli in and around the oral cavity and was shown to mediate sensitivity to volatile odorants.
A determination of the factors that mediate sensitivity to As2O3 will allow the use of this agent in such a way as to optimize therapeutic outcomes and minimize toxicity in the treatment of various malignancies.
These data are supported by the work of others in which lung cancer cell lines containing activating mutations of EGFR that mediate sensitivity to EGFR TKIs can be made resistant in the presence of HGF [ 24].
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Another, which is repressed in the aggressive flies, mediates sensitivity to the pheromone with which male flies mark their territory.
These 680 mutations may also play a role in mediating sensitivity to T20, which binds to a fusion intermediate in gp41.
However, previous studies have demonstrated that APC mediates sensitivity to cisplatin in multiple tumor types including breast cancer [ 22].
AR overexpression not only mediates sensitivity to low ligand concentrations, but has been demonstrated to convert anti-androgens such as bicalutamide and flutamide from antagonists to agonists via changes in composition of coactivators recruited to the AR promoter.
Early-life behavioral events, especially in infancy, appear to exert 'organizational' effects on the oxytocinergic system, mediating sensitivity to its effects (Feldman et al. 2013), although such processes have yet to be clearly elucidated in humans or other mammals.
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mediate attachment to
mediate tolerance to
mediate persulfate to
mediate access to
mediate interaction to
mediate hyperalgesia to
mediate adenosine to
mediate delivery to
mediate washback to
mediate resistance to
mediate damage to
mediate adhesion to
convey sensitivity to
facilitate sensitivity to
regulate sensitivity to
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