Sentence examples for mediate secretion of from inspiring English sources

The genomes of S. enterica encode two type III secretion systems (TTSS), which mediate secretion of a range of effector proteins into host cells [ 20].

The gene products of PANA_4136, PAJ_p0154 and PA-4 N455_00706 may either be T6SS effectors or mediate secretion of other effectors bound to their C-terminal extensions [ 59, 60].

Alternatively, RhsD proteins of P. ananatis may mediate secretion of other T6SS effectors which are non-covalently associated with either their N or C-terminal extension, as predicted for other PAAR proteins [ 59].

In plant pathogenic fungi ABC transporters may act as virulence factors which mediate secretion of pathogenicity factors or protecting the fungi against defense compounds produced by host plants [ 42, 43].

Here we show that ARF-GEFs BIG1-4 attheTGNhe toN to mediate secretion of newly synthesized proteins to the plasma membrane in interphase but not recycling of endocytosed plasma-membrane proteins, and that BIG3 is BFA-resistant, unlike GNOM involved in recycling to the plasma membrane.

The AVP 1a receptor is involved in blood platelet aggregation and vasoconstriction in the vessels and gluconeogenesis and glycogenolysis in the liver, 2 5 whereas the AVP 1b receptor is found in the anterior hypophysis and the Langerhans islets of the pancreas, where it mediate secretion of adrenocorticotrophic hormone, insulin, and glucagon.

The resultant membrane destabilization likely mediates secretion of periplasmic proteins required for the in vivo survival and pathogenesis of V. vulnificus.

Hence, Syntaxin 1A contributes to cuticle differentiation by controlling correct apical plasma membrane topology as well as mediating secretion of a subset of extracellular proteins required for layer organisation.

Coulter ME, Dorobantu CM, Lodewijk GA, Delalande F, Cianferani S, Ganesh VS, Smith RS, Lim ET, Xu CS, Pang S, Wong ET, Lidov HGW, Calicchio ML, Yang E, Gonzalez DM, Schlaeger TM, Mochida GH, Hess H, Lee WA, Lehtinen MK, Kirchhausen T, Haussler D, Jacobs FMJ, Gaudin R, Walsh CA. The ESCRT-III Protein CHMP1A Mediates Secretion of Sonic Hedgehog on a Distinctive Subtype of Extracellular Vesicles.

The two major domains are the functional secreted passenger, or α, domain, which may be released into the extracellular milieu or remain attached to the cell surface, and the β-domain, an integral OMP which mediates secretion of the passenger domain across the outer membrane [58].

The T6SS mediates secretion of proteins encoded within repetitive clusters of genes found distributed throughout the genome, often, though not reliably, annotated as hcp and vgrG.