Sentence examples for mediate regression from inspiring English sources
Several studies have described a unique population of macrophages with properties of both inflammatory (M1) and tissue remodeling/fibrotic (M2) macrophages, termed scar-associated macrophages, arising from recruited Ly6Chi monocytes expressing high levels of MMP13 that mediate regression of liver fibrosis in animal models [86,131-136].
IL10 is over expressed in breast tumours [ 16] and exogenous administration can mediate regression of tumour growth and breast cancer metastases in mice models [ 17].
FOXO1 also mediates regression of cardiac hypertrophy by affecting autophagy [ 79].
The role of naturally occurring cytotoxic T cells (CTLs) in mediating regression of HPV-related disease has not been proven.
Understanding the mechanisms involved through which CLA mediates regression may help identify pathways that limit or reverse human atherosclerosis.
Understanding the mechanisms involved through which CLA mediates regression may help identify endogenous pathways that limit or reverse human atherosclerosis.
Studies in animals have shown that TRAIL mediates regression of cancer xenografts without affecting normal tissues, and human phase I studies have demonstrated that TRAIL agonists are safe [ 3, 6].
Bcl-2 is anti-apoptotic in function, whereas bax is proapoptotic and it is the interaction between the two that determines the likelihood of a tumor to undergo cytotoxic drug mediated regression.
These cells could be converted into effector cells by in vitro expansion with anti-CD3mAB and IL-2 and were capable of mediating regression of established metastases following adoptive transfer (Yoshizawa et al, 1991).
Previous work has shown that CD8+ T cells are responsible for rejection of E.G7-OVA tumours and that administration of an anti-CD4 monoclonal antibody, that mediates regression of established E.G7-OVA tumours, leads to increased infiltration of CD8+ cells (Vasovic et al, 1997; Dyall et al, 1999).
Results from moderated mediation regression analyses found that masculinity and femininity fully mediated the effects of entrepreneurs' sex on business growth intentions.
