Sentence examples for mediate receptor trafficking from inspiring English sources
cbl is thought to ubiquitylate the receptor on intracellular lysine residues, perhaps through the attachment of multiple monoubiquitin moieties (Mosesson et al, 2003), to mediate receptor trafficking.
It is also possible that expression of mutant AP2σ2 subunits within the brain may directly influence neurological development, consistent with the role of the AP2 complex in mediating receptor trafficking within neuronal synapses of the hippocampus (27), a region of the brain required for memory acquisition and spatial orientation.
These complexes mediate receptor signaling, trafficking, and degradation.
The N-terminus intracellular region (cytoplasmic domain) of LOX-1 mediates receptor internalization and trafficking, potentially through intracellular protein interactions.
PLL peptide do not mediate receptor mediated adhesion rather it modulates cell adhesion via non receptor mediated electrostatic binding mechanism [4].
Regulation of AMPA receptor trafficking depends on receptor subunit composition.
Chemokines and their receptors mediate trafficking of leukocytes into the CNS in response to injury or infection.
Taxanes may partly mediate their effect in castration-resistant prostate cancer (CRPC) through disruption of androgen-receptor trafficking along microtubules.
In addition, others have reported that the C-terminal KDEL on CTA can enhance the efficiency of host cell intoxication through interactions with the KDEL receptor that mediate retrograde trafficking (for example, see J. Cell Biol. 131: 951-962), providing a potential mechanism for CT to traffic to the ER.
There is also hope that inhibiting receptors that mediate Aβ trafficking [ 4, 5] and toxicity [ 5, 6] may modify AD neurodegeneration.
To define KChIP1 vesicles and the traffic pathway followed by Kv4/KChIP1 traffic, we examined their relationship to potential SNARE (soluble N-ethylmaleimide-sensitive fusion protein-attachment protein receptor) proteins mediating the trafficking step.
