Sentence examples for mediate receptor specificity from inspiring English sources

The βγ binding surface of Gs α is largely conserved in sequence and structure to that of Gi α, whereas differences in the surface formed by the carboxyl-terminal helix and the α4-β6 loop may mediate receptor specificity.

By showing that W222R and G225D substitutions in HA mediate receptor specificity changes, we uncovered the evolutionary relationship between receptor specificity and antigenicity in the evolution of Fujian-like viruses.

Phosphorylation of several tyrosines in PI3K regulatory subunits by PI3K agonists has been previously demonstrated and phosphorylation of the inter-SH2 domain (iSH2) was suggested to mediate receptor specificity [ 28] and p110 catalytic activity [ 29].

The uniqueness of the interaction with PYL8 (and with no other PYL) provides an example of receptor specificity - an ABA receptor mediating a specific sub-network of responses.

These findings show that Env determinants for chemokine receptor specificity are distinct from those that mediate CD4-independent use of that receptor for cell fusion and provide functional evidence for multiple steps in the interaction of Env with chemokine receptors.

Joukov, V. et al. Proteolytic processing regulates receptor specificity and activity of VEGF-C.

Stevens, J. et al. Structure and receptor specificity of the hemagglutinin from an H5N1 influenza virus.

"Structural determinants for naturally evolving H5N1 hemagglutinin to switch its receptor specificity". Cell 153, no.

Determinants of glycan receptor specificity of H2N2 influenza A virus hemagglutinin.

These complexes mediate receptor signaling, trafficking, and degradation.

Receptor specificity was assessed with unlabeled exendin-3.