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Serum response factor (SRF) is a transcription factor known to mediate phenotypic plasticity in smooth muscle cells (SMCs).
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This transgenerational inheritance of DNA methylation can in some cases lead to novel epialleles and phenotypes within populations and thereby mediates phenotypic plasticity [ 8].
Community models including so-called trait-mediated indirect effects (Werner and Peacor 2003) frequently find that phenotypic plasticity mediated by species interactions (e.g., inducible defenses against predators; Tollrian and Harvell 1999) can stabilize population dynamics, even though such a stabilizing influence is not universal (Kopp and Gabriel 2006).
The clinical dilemma is the escape from gene addiction, which is mediated, in part, by phenotypic plasticity as exemplified by epithelial-to-mesenchymal transition and mesenchymal-to-epithelial transition.
DNA methylation is an epigenetic regulatory mechanism that plays an essential role in mediating biological processes and determining phenotypic plasticity in organisms.
Dr Álvarez studies phenotypic plasticity and phenotype-environment interactions as he teases apart different hypotheses about the process of local adaptation, a topic that I think is fascinating.
This oscillatory behavior could explain pathogen-mediated epimutations and excessive phenotypic plasticity.
This work reveals maternal provisioning as an organismal response to DR, demonstrates potentially adaptive intergenerational phenotypic plasticity, and identifies conserved pathways mediating these effects.
In contrast, phenotypic plasticity results in alternative complex phenotypes controlled by environmental influences rather than polymorphisms.
Isogenic phenotypic fluctuation is related to phenotypic plasticity, which is a degree of phenotype change in a different environment.
When the environmental cues that mediate phenotypic change vary both geographically and temporally, the potential exists for the evolution of population-level differentiation in the expression of phenotypic plasticity [ 3- 5].
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