Sentence examples for mediate organ damage from inspiring English sources

Liver injury may be mediated by a mitochondriopathy in reaction to cellular hyperglycemia and enhanced glycolysis and is likely to mediate organ damage [ 68].

These autoantibodies are considered to form immune complexes with their corresponding autoantigens and to mediate tissue and organ damage [ 1].

Collectively, extracellular histones function as DAMPs and mediate sterile inflammation and organ damage.

In addition, metabolic phenotypes such as insulin resistance and dyslipidaemia, which were frequently co-inherited with hypertension and may form part of the hypertension phenotype, may have inadvertently been coselected with hypertension, as well as compensatory alleles that protect against target organ damage mediated by phenotypes such as hypertension (St Lezin et al., 1999).

Hexavalent chromium-mediated oxidative stress causes severe organ damage.

Neutrophils appear to be predominant leukocytes that are important in mediating ischemia-reperfusion injury and organ damage.

LTα participates in GVHD-mediated epithelial cell apoptosis, target organ damage, and mortality and this is mediated through TNFR1 signaling [ 45].

NK cells appear to participate in mediating organ-specific damage in several murine models of autoimmunity.

Circulating mtDNA from tissue injury was recently found to be essential to mediate the systemic inflammatory response and target organ damage [ 16].

The cellular events involved in mediating organ inflammation, tissue damage, and repair are ultimately controlled at the molecular level and cannot be fully understood without consideration of the functions of the relevant genes and their products.

"Heatstroke causes organ damage, and that organ damage may persist for an unknown amount of time".