Sentence examples for mediate monocyte proliferation from inspiring English sources

The CD137 receptor/ligand system has been shown to mediate monocyte proliferation and endomitosis [11], [19] [21], DC differentiation [17], [18] and maturation [19] [21].

EGF was found also to mediate monocyte chemotaxis and macrophage proliferation [ 18].

Initial stage (24 48 h) is characterized by active monocyte proliferation mediated in part by RANKL-stimulated release of autocrine factors.

Similarly, pitavastatin has been shown to have effects on inflammation and immunomodulation that may be mediated, in part, by dose-dependent inhibition of monocyte proliferation through down-regulation of the chemokine receptors CCR2 and CCR5 [53], inhibition of lysophosphatidic acid-induced aortic smooth muscle cell proliferation and expression of MCP-1 [54].

In another randomized research, HCO hemofiltration restored the monocyte proliferation capacity of septic patients, probably by eliminating immunomodulatory mediators [31].

Thus, the small increase in the survival at 24 h may reflect increased metabolic activity of the cells at 24 h post isolation (freshly isolated monocytes) and 24 h after thawing (cryopreserved monocytes) and does not relate with monocyte proliferation.

These antibodies stimulate monocyte proliferation, and rotavirus infection might explain some early steps in the cascade of immune cell proliferation.

Both monocyte proliferation and death have been previously reported to be affected by RANKL [11].

33 As a result cytokine (TNFα and IL-1β) production by monocytes was inhibited while monocyte proliferation remained unaltered.

Importantly, the cytokines demonstrated to regulate monocyte and osteoclast numbers exhibited significant overlap, further confirming that initial monocyte proliferation is important for successful osteoclastogenesis.

Inflammatory (M1) macrophages secrete TNF-α and IL-1β mediating monocyte recruitment and removal of necrotic cells at early stages after the initiating event.