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SEA/E-120 is likely to have a low toxicity due to its reduced capacity to mediate killing of MHC class II expressing cells.
Histatins mediate killing of C. albicans by causing leakage of intracellular potassium ions and ATP [9], [10].
We extended the above observations to see if T cells recruited by RANTES and IP-10 would mediate killing of mycobacteria inside macrophages.
In contrast, macrophage apoptosis has been described to mediate killing of obligate intracellular Coxiella burnetti in IFN-γ activated THP-1 cells [46].
We first investigated whether, T cells activated by IFN-γ and IL-12 conditioned BCG infected CFP10-DCs would mediate killing of M. tb H37Rv inside macrophages.
Combination of these two inhibitors had an additive effect on inhibiting NK cell mediate killing of gene transduced cells.
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The field of cancer immunotherapy has expanded rapidly in the past few years, with many new approaches entering the clinic for T cell mediated killing of tumors.
We then evaluated the effectiveness of drug-resistant immunocompetent cell mediated killing of tumor cells in the presence and absence of chemotherapy.
In our endeavor to investigate the role of nitric oxide mediated killing of the P. vivax parasite in the An.
Our findings suggest that HLA-E is a key player in the regulation of NK cell mediated killing of ECs.
Blocking L-type and R-type VGCC in DCs, primed T cells that mediated killing of M. tuberculosis inside macrophages.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com