Sentence examples for mediate joint from inspiring English sources

One critic, Philip Tetlock, a psychologist at the University of California, Berkeley, said he had found prominent research groups and scholars willing to mediate joint experiments.

NGF may also mediate joint damage [ 6].

Because MMPs mediate joint destruction, MMP inhibitors are now used as therapeutics for mild rheumatoid arthritis.

Neutrophils [ 73] and mast cells [ 74] are both required as effector cells to mediate joint destruction.

Rheumatoid synovial fibroblasts (RASFs) mediate joint inflammation and destruction in rheumatoid arthritis (RA).

Pannus is extremely vascular, providing portals of entry for effector cells to enter the joint from the circulation and mediate joint destruction via autocrine and paracrine mechanisms.

The goal of the present study was to investigate whether IL-18 mediates joint destruction in vivo, directly or via induction of other cytokines.

Inflammatory cytokines including TNF-α, IL-1 and IL-17 have a clearly documented role in mediating joint inflammation in RA.

Korganow and colleagues identified ICs involving glucose-6-phosphate isomerase (GPI) as mediating joint inflammation in their spontaneous K/BxN model [ 15].

Moreover, TNC is required for the induction of IL-17 in inflamed murine joints [ 9], a cytokine that directly mediates joint tissue degradation by activating bone resorbing osteoclasts, inhibiting cartilage matrix synthesis and inducing proteases [ 30].

In order to investigate the impact of FAP on TNF-mediated joint destruction, we next analyzed whether the lack of FAP leads to altered histological changes in the arthritic joints of hTNFtg mice.