Sentence examples for mediate its uptake from inspiring English sources

Apart of HSPGs, several cell surface proteins have been shown to bind heparanase and mediate its uptake.

An Arg-His-Asp sequence in Aβ was shown to be recognized by α5β1 integrin and mediate its uptake and degradation [47].

The oviduct must be prepared to transport each oocyte released from the ovary to the uterus, to mediate its water uptake and eggshell crosslinking, and to position it for efficient fertilization (reviewed in Spradling, 1993).

Motivated by our previous findings that Stx can mediate its own uptake and affect signaling, we set out to investigate if Stx, although binding to a glycolipid, was able to increase the formation of endocytic clathrin coat structures at the plasma membrane and if such increase in clathrin coats might be mediated by signaling through the Syk kinase.

In humans the megalin receptor can bind siderocalin (and its siderophore payload) and mediate its intracellular uptake [ 392].

The most acceptable explanation for the protective effects of HDL-C on cardiovascular disease is its action to mediate the uptake of peripheral cholesterol and return it to the liver for excretion into the bile and gut, termed 'reverse cholesterol transport', 20 a process which has been postulated to explain how HDL-C protects against atherosclerosis.

First, it is argued that a greater specificity of measurement is needed as PA undertaken for different purposes and/or at different levels of intensity is predicted by different determinants, and its uptake mediated by different factors.

Low-density lipoprotein (LDL) is the major cholesterol carrier in plasma and its uptake is mediated by LDL-receptor (LDL-R), a glycoprotein overexpressed on the surface of cancer cells.

Its uptake is mediated by a fructose-specific PTS-system [ 55].

2. Identification of new pathways that mediate the uptake and transcytosis of low density lipoprotein (LDL) and determining how LDL receptor influences vascular disease.

(TIF 189 kb) Additional file 7: OsGLRs mediate ion uptake in bacteria.