Sentence examples for mediate its effects from inspiring English sources

The stimulatory effect of low concentrations of rolipram on neurite outgrowth suggests that it might mediate its effects on neurite outgrowth via Rho.

This effect of prior stress on later vulnerability is illustrated in Figure 2, 1 and it is thought to mediate its effects through opioid-related mechanisms (Overmier & Murison, 1994).

Its multiple ligands and diverse roles attest to the need for exquisite control over the signaling pathways that mediate its effects.

Cortical spreading depression may mediate its effects in part by altering the permeability of the blood brain barrier via activation of matrix metalloproteinases, a family of neutral metalloproteases [113].

Conclusion: fucoidan is a more potent anti-proliferative polysulphated polysaccharide than heparin and may mediate its effects through inhibition of the mitogen-activated protein kinase pathway in a similar manner as heparin.

Clearly, there exist multiple targets for H2O2 to mediate its effects in specific cells and tissues.

The resulting pool of free vimentin may mediate its effects on motility, adhesion, cell signaling, and cell survival.

These observations are consistent with suggestions that podocalyxin may mediate its effects through interactions with other extracellular or membrane proteins.

HA may mediate its effects via activation of IL-8 related signaling pathways that may play a role in ruffled-border formation and subsequent bone degradation [40], [41].

We used yeast 2 hybrid screens to identify novel binding partners of R-Ras that could mediate its effects on integrin function.

Using a yeast two-hybrid approach we sought to identify novel R-Ras binding proteins that might mediate its effects on integrins.