Sentence examples for mediate its binding from inspiring English sources
PGRN is a cysteine-rich protein and proper folding of the protein is critical to mediate its binding to TNFR.
These protein fragments are considered antibody-mimetic because, like antibodies, each protein fragment is composed of a constant region, which stabilizes the overall protein folding, and multiple variable regions that mediate its binding to a specific target.
Finally, the tandem repeats of MYM-type zinc fingers of ZNF198 mediate its binding to both LCH and sumoylated HDAC1.
Thus, zinc fingers 8 and 9 of ZNF198 mediate its binding to LCH, whereas additional zinc fingers are required for the binding of ZNF198 to HDAC1-SUMO2.
In order to determine the specific regions on LASP-1 that mediate its binding to CXCR2-CTD, different domains of LASP-1 were expressed as LIM, LIM-NR, or NR-SH3 domain in 293-parental cells.
Based on the studies showing that the 40s loop of CCL5 mediates its binding to glycosaminoglycans (GAG), we analyzed the roles of GAG in regulating CCL5 secretion.
Our study is the first to report the erythrocyte binding activity of PfRH2a/b and delineate a region of the native protein that mediates its binding with erythrocytes.
In conclusion, we have found that, despite the evolutionary diversification of the MAGE family, the characteristic hydrophobic surface shared by all MAGE proteins from yeast to humans mediates its binding to NSE4/EID proteins.
We have found that, despite the evolutionary diversification of the MAGE family, the characteristic hydrophobic surface shared by all MAGE proteins from yeast to humans mediates its binding to NSE4/EID proteins.
LBP binds to Gram-negative bacteria via the lipid A part of the lipopolysaccharide (LPS) which mediates its binding to the CD14 cellular receptor molecule presented by monocytes and macrophages [12], [13].
Our data also demonstrate that the N-terminal region of HIV-1 Vif mediates its binding not only to the target molecules A3G and A3F but also to A3C and A3DE.
