Sentence examples for mediate internalization of from inspiring English sources

Several mechanisms have been described to mediate internalization of antigens into APCs, including phagocytosis, macropinocytosis, receptor-mediated endocytosis and caveolar endocytosis.

Paquet, S. et al. PrPc does not mediate internalization of PrPSc but is required at an early stage for de novo prion infection of Rov cells.

There are several endocytic pathways that can mediate internalization of cell surface receptors, some of which are dependent on receptor ubiquitination [17], [18].

One of the key functions of βarr2 at the plasma membrane is to mediate internalization of agonist-activated GPCRs through clathrin-coated pits.

Gentamicin protection assays showed, that CEACAM1, but not other members of the CEACAM-family, was able to mediate internalization of Opa protein-negative meningococci (Fig. 2A).

In particular, CEACAM1, CEACAM3, CEA (the product of the CEACAM5 gene) as well as CEACAM6 have been reported to bind to neisserial OpaCEA proteins, and to mediate internalization of the pathogens [25], [26].

Henley, J. R., Krueger, E. W., Oswald, B. J. & McNiven, M. A. Dynamin-mediated internalization of caveolae.

Stamatovic, S. M., Keep, R. F., Wang, M. M., Jankovic, I. & Andjelkovic, A. V. Caveolae-mediated internalization of occludin and claudin-5 during CCL2-induced tight junction remodeling in brain endothelial cells.

We show that Pk participates in negative feedback by mediating internalization of PCP complexes containing the transmembrane components Van Gogh (Vang) and Flamingo (Fmi), and that internalization is activated by oppositely oriented complexes within clusters.

We recently demonstrated that megalin binds and mediates internalization of ANG II.

Thus it appears that the function of all arrestin family members in mediating internalization of G protein-coupled receptors is regulated by distinct phosphorylation/dephosphorylation mechanisms.