(6) Cell-surface glycans are poised to mediate intercellular communication, 7) including pathogen recognition, and to distinguish self from non-self immunologically.
Extracellular vesicles (EVs) are naturally occurring membrane particles that mediate intercellular communication by delivering molecular information between cells.
aGPCRs have large alternatively spliced extracellular regions (ECRs) that likely mediate intercellular signaling; however, the precise roles of ECRs remain unclear.
Dear Editor, Exosomes are cup-shaped small (30 150 nm) extracellular vesicles with the structure of lipid bilayer membrane (Tkach and Thery, 2016) containing proteins, mRNAs and microRNAs that mediate intercellular communication (Valadi et al., 2007).
MPs mediate intercellular communication (Zhao et al., 2016; Tian et al., 2015; Budnik et al., 2016; Zappulli et al., 2016), resulting in secondary injures such as systemic coagulopathy and inflammation after TBI (Zhao et al., 2016; Tian et al., 2015).
Furthermore, exosomes carrying miRNA are believed to mediate intercellular signalling between tumour cells and bystander cells (Melo et al. 2016; Yang et al. 2011; Umezu et al. 2013; Sánchez et al. 2015).
For example, microvesicles may mediate intercellular communication by transporting bioactive lipids, mRNA, or proteins between cells.
The determination of cellular mechanisms and pathways leading to intercellular recognition and "oncologic trogocytosis" with Hospicells could lead to the identification of novel therapeutic approaches targeting intercellular interactions.
Ephrins are cell-surface signaling molecules that bind in trans to Eph receptor tyrosine kinases to mediate intercellular communication.
Immunological synapses mediate intercellular communication between T cells and target cells, both in vitro and in vivo.
