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These observations, together with the documentation of a limited lateral diffusion of fluorescent membrane proteins occurring between the plasma membranes of TNT-connected cells, led to the proposal that TNT mediate intercellular membrane continuity (Fig. 3a) (Gerdes et al. 2007; Rustom et al. 2004).
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Extracellular vesicles (EVs) are naturally occurring membrane particles that mediate intercellular communication by delivering molecular information between cells.
The coronavirus S protein is known to mediate both virion-cell membrane fusion, and intercellular membrane fusion [22], [30] [33] and in the present study we have shown that purified inactivated virions are also fusion-competent.
Dear Editor, Exosomes are cup-shaped small (30 150 nm) extracellular vesicles with the structure of lipid bilayer membrane (Tkach and Thery, 2016) containing proteins, mRNAs and microRNAs that mediate intercellular communication (Valadi et al., 2007).
MPs are small membrane-bound particles that originate from activated and dying cells and mediate intercellular communication.
To elucidate the primary means through which EVs mediate intercellular communication, we characterized their ability to encapsulate and deliver different types of macromolecules from transiently transfected cells.
Cell surface proteins mediate intercellular recognition and signal transduction.
For example, microvesicles may mediate intercellular communication by transporting bioactive lipids, mRNA, or proteins between cells.
Ephrins are cell-surface signaling molecules that bind in trans to Eph receptor tyrosine kinases to mediate intercellular communication.
Immunological synapses mediate intercellular communication between T cells and target cells, both in vitro and in vivo.
Thus these ACs predominantly mediate intercellular communication [ 1].
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